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Tag: Gene editing

New Gene-Editing Technique Can Alter Genome Without Cutting DNA

Researchers developed a CRISPR system that eliminated the need to cut the genome to insert new DNA sequences. Called CAST, the new system can enable safer and more accurate gene-editing.

Biotech June 15, 2019

Researchers Introduce New Model That Could Explain Autism

Researchers genetically edited macaque monkeys to study autism in the hopes of developing new treatments for humans. During the experiment, the macaque monkeys exhibited similar behavioral patterns to humans who have the same mutations.

Animals June 13, 2019

CRISPR-Modified Viruses Could Be Next Potent Weapon Against Drug-Resistant Bacteria

Scientists are looking at CRISPR gene-editing technology to develop a treatment to antibiotic-resistant bacteria or superbugs. A company called Locus Biosciences claimed that it has a 'living antibiotic' made up of viruses that only attack harmful pathogens.

Public Health May 24, 2019

Biohacker Who Injected Himself With Gene-Editing Tech Now Under Investigation By Health Officials

A celebrity biohacker was summoned by California's Department of Consumer Affairs to discuss a complaint against him. The former NASA scientist and the CEO of The Odin was accused of practicing medicine without license.

Public Health May 21, 2019

Crispr Food Will Be Available Within 5 Years, Says Geneticist

Food created from the gene editing tool Crispr is making its way to the supermarket relatively soon. According to the geneticist who helped invent the Crispr tool, the next five years will see an influx of such products.

Feature | Science April 22, 2019

Biomedical Engineers Want To Create 'Hairpins' To Improve Accuracy Of CRISPR

Researchers developed a new method in which the guide RNA is extended to it folds onto itself and create an unbreakable lock. Only the correct DNA sequence can unlock the guide RNA, reducing the risk of off-target activity.

April 17, 2019

Albino Lizard Is World's First Gene-Edited Reptile

A group of scientists has created the first gene-edited reptiles in four albino lizards. Before now, reptiles have been rather ignored when it comes to developmental genetics.

Animals April 11, 2019

Scientists Use Spider Genes And Bacteria To Create Mass Production Process For High-Strength Silk

U.S. researchers developed a novel way of mass-producing spider silk using the animal’s genome and bacteria. If it becomes successful, it will have various applications such as spacesuit repair and bioproduction in space.

Material Science April 4, 2019

Gathering Of Top Experts Urge Moratorium On Gene-Editing Experiments Involving Babies

Two of the principal inventors of the CRISPR system signed a new moratorium on germline editing. The move was a direct response to a controversial experiment by Jiankui He in China four months ago.

Public Health March 14, 2019

CRISPR-Edited Babies Might Have Improved Brain Functions

Could the babies who were genetically modified to be immune to HIV receive an enhanced brain function because of the procedure? A study revealed that the gene associated with susceptibility to HIV plays a major role in memory and cognition.

February 22, 2019

A Single CRISPR Treatment Can Show Significant Benefits In Mice With DMD

A team of researchers found that a single CRISPR therapy corrected DMD in mice for a year. They hope that their study will pave the way for the development of an effective treatment for humans.

Biotech February 20, 2019

Nobel Prize Winner Craig Mello Reportedly Aware Of He Jiankui's Gene-Edited Babies Long Before Experiment Became Public

E-mails obtained by the AFP suggested Nobel laureate Craig Mello was long aware of He Jiankui's work on gene-edited babies. Mello objected to the project but remained a scientific adviser to He’s Direct Genomics company.

Feature | Health January 29, 2019

Chinese Scientists At It Again With Gene-Edited Monkeys

Five gene-edited monkey clones were born at the Institute of Neuroscience of the Chinese Academy of Sciences in Shanghai, China. The latest research is intended to back efforts in testing and developing drugs for the treatment of various human diseases in the years to come.

Animals January 24, 2019

Investigation Shows CRISPR Researcher He Jiankui's Work On First Gene-Edited Babies Broke The Law

Chinese CRISPR Scientist He Jiankui was found to have illegally edited the genes of the babies. Law authorities said he and others involved will be dealt with accordingly.

Biotech January 21, 2019

Geneticists Are Considering Creating A Spicy Tomato

New research suggests that tomatoes may be engineered to produce capsaicinoids using the latest gene-editing techniques. Capsaicinoids have important medical uses, specifically in the treatment of cancer.

Healthy Living/Wellness January 9, 2019

Chinese Scientist He Jiankui Who Created World's First CRISPR Babies May Face Death Penalty

The Chinese scientist who was instrumental to the birth of the world's first genetically edited babies has far worse predicament than earlier thought. He could face corruption and bribery charges, which are punishable by death in China.

Feature | Science January 7, 2019

Gene Editing May Help Obese People Who Want To Lose Weight

A new study by scientists from the University of California, San Francisco showed how CRISPRa can be used to amplify the genes that curb human's appetite for food. The researchers believe this new gene-editing technique could tackle the obesity crisis.

Public Health December 15, 2018

Scientists Figure Out Simple Rules For CRISPR Genome Editing In Human Cells

A new set of rules that could predict the outcome of gene editing might pave the way for the wider use of CRISPR/Cas9 to treat diseases. According to scientists, after a thorough analysis, they found a pattern that foresees mutations.

Public Health December 14, 2018

Chinese Scientist He Jiankui Who Claimed He Edited Babies' Genes Is Missing

The Chinese scientist who used CRISPR gene-editing tool to edit the DNA of twin babies is missing. Is he detained by China’s government? Pictured is He Jiankui at the Second International Summit on Human Genome Editing in Hong Kong.

Biotech December 4, 2018

WHO Considering Panel On Gene Editing Ethics

The World Health Organization expressed the need to regulate gene editing after a Chinese scientist had admitted to manipulating human embryo. A panel will be created to talk about the issue.

December 4, 2018

Scientist Responsible For 'CRISPR' Babies Speaks Out And Defends Research

The scientist who claimed to have made the first genetically edited baby has defended the procedure at a conference in Hong Kong. In his speech, he said that he is proud of what he has done.

November 29, 2018

Chinese Scientist Says Gene Edited Babies Now A Reality

A scientist from China admitted that he has genetically edited twin girls to become immune to HIV/AIDS. However, the process has serious implications that might put the children and their future descendants at risk.

November 26, 2018

Healthy Mouse Brood Born From Same-Sex Parents Via Stem Cells And Gene Editing

Stem cell technology and gene editing allowed scientists to create a healthy brood of baby mice from same-sex parents. It was also easier to create the baby mice from two females compared to two male parents.

Feature | Science October 11, 2018

Scientists Want To Use Gene Editing To Turn Wild 'Groundcherry' Into The Next Strawberry

Researchers published a study proposing the use of CRISPR gene-editing tool to make ground cherries, an orphan plant, ready for the supermarket. Breeding plants for large-scale farming usually take a decade to thousands of years.

Earth/Environment October 3, 2018

Autism Traits Can Be Genetically Edited Out Using CRISPR

Using CRISPR-Gold method, researchers were able to reduce autism symptoms in mice with fragile X syndrome. What makes this method different and better than other ways of delivering Cas9 into the body?

Neuroscience June 27, 2018

Scientists Use Gene Editing Tool CRISPR To Engineer Pigs Immune To Costly PRRS Disease

Using CRISPR, scientists removed a small section of a gene that makes pigs vulnerable to PRRS, a disease that causes costly pig deaths and reduced productivity. Scientists said that the gene-edited animals showed complete immunity.

Animals June 25, 2018

CRISPR Gene Editing Could Cause Cancer According To Separate Studies

Two individual studies conducted by separate teams of researchers found that breakthrough CRISPR gene editing technology could boost the risk of cancer in humans. Specifically, the teams looked into how the protein called p35 responded to the newly edited DNAs.

Biotech June 12, 2018

Scientists Are Editing Rice Genes To Make Them Produce More

Scientists have created the perfect rice plant that is not only slightly more vulnerable to environmental factors but able to produce up to 31 percent more grain. Ethical questions on gene editing remain, however.

Biotech May 29, 2018

CRISPR Gene Editing Technology Reduces Blood Cholesterol Levels In Animal Study

Using a new delivery technique, Biomedical engineers at Duke University reduced blood cholesterol levels in mice. The result became the first time researchers delivered CRISPR/Cas9 repressors for targeted therapeutic gene silencing in adult animal models.

Biotech April 29, 2018

Journal Retracts Paper That Said CRISPR Is Dangerous

A controversial paper that claimed the gene-editing software CRISPR is dangerous retracted its claims that had caused panic. The software is seen as a major stepping stone in fighting diseases.

Biotech April 2, 2018

Gene-Editing Tool CRISPR Used To Detect Infections Such As Dengue, Zika Virus, HPV

New diagnostic tools have been developed using the CRISPR gene editing tool. A bunch of researchers were able to come up with new CRISPR variants that can diagnose certain diseases, detect viruses, and even record a cell’s exposure to chemicals.

Public Health February 16, 2018

CRISPR Gene Editing Tools May Not Work On Most Humans

CRISPR has been touted as the next step for human evolution, but a new paper may cast doubt on its effectiveness. Due to immune responses, the gene editing tool may not work on most humans.

Biotech January 9, 2018

CRISPR Without Scissors: Modified Gene Editing Tool Can Edit DNA Without Cutting It

A CRISPR system that lacks scissors to cut DNA strands can change the gene's behavior without making direct modifications on the DNA. How does this modified gene editing tool work?

Biotech December 9, 2017

New Editing Technique Could Life-Saving Treatment For Thousands Of Diseases

Harvard University scientists have come up with two breakthrough finds using the CRISPR-Cas9 technology. The techniques can be used in the future for curing or treating various diseases.

Biotech October 27, 2017

CRISPR Gene-Editing Tool Creates Pigs With 24 Percent Less Body Fat

Using CRISPR, scientists in China created pigs with the UPC1 gene. Besides having less body fat, the genetically modified animals also have other characteristics that can benefit pig farmers.

Feature | Science October 25, 2017

Scientists Create First Mutant Ants Using CRISPR Gene Editing To Study Social Behavior

Researchers used CRISPR to remove a gene in ants that allow them to sense the pheromones they also use to communicate with other ants. Without it, the mutant ants were less sociable, were strange in behavior, and had altered brain shapes.

Animals August 11, 2017

Scientists Successfully Use CRISPR-Edited Skin Grafts To Treat Type-2 Diabetes And Obesity

Scientists grafted genetically edited human skin cells to treat type-2 diabetes and prevent obesity in mice. The removable patches could be a viable replacement for insulin shots.

Biotech August 6, 2017

Scientists Successfully Use CRISPR To Snip Genetic Defect From Human Embryo

Hereditary diseases may soon be a thing of the past. Scientists from OHSU successfully corrected a faulty gene that leads to fatal heart disease using CRISPR.

Biotech August 5, 2017

Small Study Finds Fatal Flaw In Gene Editing Tool CRISPR

The CRISPR-Cas9 gene editing technique may lead to unwanted genetic mutations, warns a new study. Researchers sequenced the whole genome of mice previously treated with CRISPR gene editing for genetic blindness and found it caused unpredicted changes in their DNA.

Biotech May 31, 2017

Cure For HIV May Already Exist: Here's How CRISPR Gene-Editing Technology Can Kill AIDS-Causing Virus

In experiments with mice, researchers found that the gene editing technology CRISPR works for active and dormant forms of HIV. How does treatment with this controversial technique differ from currently available drugs?

Biotech May 4, 2017

Gene Editing Can Produce Hornless Cows And Boost Livestock Production - Here’s How

An animal geneticist highlights the benefits of gene editing in complementing traditional animal breeding techniques. The move, although hampered by current regulations, is seen to produce hornless cows and disease-resistant farm animals.

Animals February 21, 2017

Broad Institute Wins Patent To CRISPR: Here's Why It Matters

Broad Institute retains the lucrative rights to gene-editing technique CRISPR after a U.S. patent office’s ruling found no 'interference' on the patent. On the losing side is the University of California, Berkeley, considered as the home of this particular technology.

Biotech February 16, 2017

New Software Simplifies CRISPR Methodology For Gene Editing

Researchers at the Karolinska Institutet and University of Gothenburg in Sweden recently generated the software called Green Listed to facilitate the use of CRISPR-Cas9, making information texts and films available for free non-profit and academic use.

Biotech January 5, 2017

CRISPR Has An Off Switch: Researchers Identify Anti-CRISPR Proteins To Inactivate Gene Editing System

CRISPR holds a lot of promise but there’s definitely room for improvement. Researchers have identified anti-CRISPR proteins that can act as an off switch for the gene editing system, making it safer to use.

Biotech December 31, 2016

Chinese Scientists Test CRISPR-edited Genes On Humans For The First Time

For the first time, research conducted in China has employed the CRISPR gene-editing technique to treat patients with cancer. Should the trial end with no significant side-effects, the method could become widely used.

Medicine November 16, 2016

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